| 书目名称 | Murine Models, Energy Balance, and Cancer | | 编辑 | Nathan A. Berger | | 视频video | | | 概述 | Provides compilation of major experimental mouse model systems for future preclinical research on energy balance and cancer.Identifies how models are further enhanced by technology to identify DNA seq | | 丛书名称 | Energy Balance and Cancer | | 图书封面 |  | | 描述 | .This volume provides a transdisciplinary and translational review of many of the leading murine models used to study the mechanisms, mediators and biomarkers linking energy balance to cancer. It provides a review of murine models that should be of interest to basic, clinical and applied research investigators as well as nutrition scientists and students that work in cancer prevention, cancer control and treatment. .The worldwide obesity pandemic has been extensively studied by epidemiologic and observational studies and even, in some cases, by randomized controlled trials. However, the development and control of obesity, its comorbidities and its impact on cancer usually occurs over such long periods that it is difficult, if not impossible to conduct randomized controlled trials in humans to investigate environmental contributions to obesity, energy balance and their impact on cancer. In contrast, model organisms, especially mice and rats, provide valuable assets for performing these studies under rigorously controlled conditions and in sufficient numbers to provide statistically significant results. In this volume, many of the leading and new murine models used to study the mecha | | 出版日期 | Book 2015 | | 关键词 | Mouse models; epigenetic influences; genetic engineering; leptin; obesity and cancer | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-16733-6 | | isbn_softcover | 978-3-319-38355-2 | | isbn_ebook | 978-3-319-16733-6Series ISSN 2199-2622 Series E-ISSN 2199-2630 | | issn_series | 2199-2622 | | copyright | Springer International Publishing Switzerland 2015 |
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发表于 2025-3-21 16:55:03
