| 书目名称 | Mouse Models for Drug Discovery | | 副标题 | Methods and Protocol | | 编辑 | Gabriele Proetzel,Michael V. Wiles | | 视频video | | | 概述 | Provides an excellent source for understanding the strength of the mouse as a model.Includes essential background about mouse genetic engineering.Covers the classic outbred and inbred mice as well as | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .As the drug discovery process shifts more and more toward specifically targeting pathways and molecules, model systems continue to increase in importance, and the mouse, with its versatility, ease of use, and remarkable similarity to the human genome, has clearly risen to the forefront of animal model studies. In .Mouse Models for Drug Discovery: Methods and Protocols., experts in the field present some background for those less familiar with mice as experimental model platforms as well as a collection of techniques involving general methods as well as specific disease topics such as type 1 and 2 diabetes, cardiovascular disease, arthritis, skin disorders, cancer, the use of behavioral models for depression and anxiety, neurodegenerative diseases, neuromuscular diseases, and infectious diseases. Written in the highly successful .Methods in Molecular Biology.™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls...Authoritative and easy-to-use, .Mouse Models for Drug Discovery: Methods and Protocols. wi | | 出版日期 | Book 2010 | | 关键词 | Disease topics; Experimental design; Genetically engineered; Genomes; Inbred and outbred mice; Laboratory | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-60761-058-8 | | isbn_softcover | 978-1-4939-6121-4 | | isbn_ebook | 978-1-60761-058-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 2010 |
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发表于 2025-3-21 17:20:38
