Titlebook: Microfluidics in Pharmaceutical Sciences; Formulation, Drug De Dimitrios A. Lamprou,Edward Weaver Book 2024 American Association of Pharmac

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Microfluidic Manufacturing of Polymeric Nanoparticles, as on poly(lactic-co-glycol acid) (PLGA) and its derivatives such as poly(lactic-co-glycol acid)-co-polyethylenglycol (PLGA-PEG) The preparation methods are described and revised, highlighting the process parameters..Eventually, scale-up at industrial production methods are introduced and discussed

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Microfluidic Approaches for Gene Delivery and Therapy,sage of materials, high throughput, high customizability, and flexibility. Microfluidic devices have been developed to deliver a wide range of different payloads into different cell types with the highest level of precision and efficiency. In this chapter, we review recent advances in microfluidic a

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Microfluidic Flow Cytometry,s methods employed to manipulate and focus cells within flowing streams. This is followed by a discussion of contemporary optical detection systems and how these may be integrated within microfluidic platforms. We emphasize the significance and opportunities associated with imaging flow cytometry, d

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Application of Microfluidics in Drug Development,lined and automated workflows. In this chapter, we highlight the versatility of microfluidic platforms in accelerating drug development and explore the application of microfluidics in three key stages of drug development process: drug synthesis, drug screening, and drug evaluation.

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Microfluidic Technologies for Precise Drug Delivery,n preparing various DDSs, including microparticle and nanoparticle (NP) systems of lipid and polymer matrices. This review provides a summary of recent therapeutic applications of novel DDS produced or administered with the aid of cutting-edge microfluidic devices. The covered applications will part

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Microfluidics for Formulation and Scale-Up Production of Nanoparticles for Biopharma Industry,id-based and polymeric nanoparticles. Scale-up productions are also discussed, addressing their importance, strategies, and associated challenges. Additionally, the characterization of nanoparticles is considered, encompassing in vitro and in vivo properties, providing insights into nanoparticles’ s

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