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Titlebook: Microfluidic and Compartmentalized Platforms for Neurobiological Research; Emilia Biffi Book 2015 Springer Science+Business Media New York

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Multi-compartment Neuron–Glia Coculture Microsystem cells that allow detailed investigation into axon–glia interactions and spatial regulation of functions. Here, we describe a multi-compartment neuron–glia coculture microsystem platform where axons can be fluidically and physically isolated from neuronal somata and dendrites so that interactions be
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Compartmentalized Microfluidic Platforms as Tool of Choice to Study the Interaction Between Neurons research. Compartmentalized microfluidic devices, initially applied in the neuroscience field for the simplest biochemical tests, is presently used at the most complex assays such as cocultures for developmental and regeneration studies. Excitingly, these devices have emerged as a potential tool to
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Compartmentalized Microfluidics for In Vitro Alzheimer’s Disease Studies chambers can be expanded to induce co-pathological cell cultures, where one cell population expresses a specific disease state, while being in direct-cell or metabolic contact to a second or third unaffected cell population. A typical example for co-pathological cell states in the brain is the well
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Selective Biochemical Manipulation of Twin Neuronal Networks on Microelectrode Arraysharmacological assays. Here, we describe the fabrication and the use of a device for long-term growth of twin neuronal networks and for their controlled biochemical stimulation. The device is formed by a PDMS microfluidic chamber coupled to a flat Microelectrode Array (MEA), which provides the elect
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Bryson M. Brewer,Donna J. Webb,Deyu Liex geometries with tight tolerance requirements where large distortion is undesirable. The understanding and characterization of NSRS in milled aluminum parts is important and should be included in the design and manufacturing process. There exists a variety of experimental tests for characterizing
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Jonathan West,Ngoc-Duy Dinh,Heike Hardelauf,Ya-Yu Chiang,Tracey A. Newman,Mariana Vargas-Caballero,Ato effectively identify the modal parameters. In this study, the MIMO concept is extended to the time domain for system identification of systems with modal interference. When performing a modal analysis of a structural system with close modes or high damping, the results of identification may be po
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