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Titlebook: Microfluidic and Compartmentalized Platforms for Neurobiological Research; Emilia Biffi Book 2015 Springer Science+Business Media New York

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Katherine A. Southam,Anna E. King,Catherine A. Blizzard,Graeme H. McCormack,Tracey C. Dickson
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Book 2015nd Compartmentalized Platforms for Neurobiological Research. provides practical skills needed to fabricate, use microfluidics and compartmentalized platforms with neuronal cell cultures as well as the strengths of these exciting devices and their precious contribution in the field of Neuroscience..
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Asymmetric Genetic Manipulation and Patch Clamp Recording of Neurons in a Microfluidic Chipdies that require specific expression of for example optogenetic tools in presynaptic neurons or for studying the entry of pathogenic particles, such as viruses or oligomers of misfolded proteins, into presynaptic structures.
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Development of a Compartmentalized Biochip for Axonal Isolation and Neuronal-Circuit Formation at thtudy glia–neuron interaction at the single-cell level is necessary. In this chapter we describe a biochip-microfabrication technique and a unique laser cell-micropatterning system for creation of a compartmentalized, axon-isolating, polarized neuron-growth platform at the single-cell level.
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Compartmentalized Microfluidic Platforms as Tool of Choice to Study the Interaction Between Neurons tandardize the major proceedings to ensure the success of the coculture model for neurons and osteoblasts and further recommend the qualitative and quantitative analysis for two- or three-dimensional cocultures.
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Selective Biochemical Manipulation of Twin Neuronal Networks on Microelectrode Arraysally independent but fluidically connected neuronal networks can be grown. This platform improves biological comparability between cultures and allows to perform selective and temporally controlled stimulations to neurons, running parallel pharmacological tests on the same device.
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