书目名称 | MicroRNA and Cancer | 副标题 | Methods and Protocol | 编辑 | Wei Wu | 视频video | | 概述 | Highlights the fast-growing field of microRNAs with the pivotal, cutting-edge knowledge of its relation to cancer biology.Provides contributions from experts, including their invaluable experience in | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | The tiny microRNAs (miRNAs) can have huge impacts on the regulation of a variety of genes and play crucial roles in the fundamental cellular processes.Recent miRNA studies change the landscape of cancer genetics by scrutinizing the alterations of genome-wide miRNA expressions in most common cancers and their regulatory functions during the development of cancer. The connections between miRNAs and cancer are widespread enough to warrant more comprehensive investigations in the systems biology perspective.In MicroRNA and Cancer: Methods and Protocols, internationally renowned experts provide the latest miRNA knowledge, the various techniques and methodologies currently available for cancer research application.Ranging from the fundamental concepts to practical applications, this book presents:• Overview of microRNA biogenesis, computational prediction of new miRNAs in the cancer genome, and miRNA-based therapeutic approaches for cancer treatment• Detailed experimental protocols in miRNA detection with novel and high-throughput technology, miRNA library cloning, miRNA epigenetic regulation, and miRNA pathway study• Stepwise computational and bioinformatic procedures for miRNA complex | 出版日期 | Book 2011 | 关键词 | Biogenesis; Cancer biomarkers; Cancer genome; Computational prediction; Epigenetic regulation; Library co | 版次 | 1 | doi | https://doi.org/10.1007/978-1-60761-863-8 | isbn_softcover | 978-1-4939-5774-3 | isbn_ebook | 978-1-60761-863-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC 2011 |
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