书目名称 | MicroRNA Detection and Pathological Functions | 编辑 | Xueji Zhang,Haifeng Dong,Yaping Tian | 视频video | | 概述 | Provides a comprehensive summary of current techniques for miRNA detection.Describes both the technical and clinical aspects of miRNA.Addresses the promising clinical applications of miRNA, emphasizin | 丛书名称 | SpringerBriefs in Molecular Science | 图书封面 |  | 描述 | .This book summarizes microRNA (miRNA) biology in a variety of pathological processes, emphasizing the significant potential applications of miRNA in diagnostics and prognostics, as well as novel drug targets. The conventional techniques used for miRNA detection including standard PCR, Northern blotting, microarray and clone methods are addressed. Recent emerging strategies in miRNA detection and quantification with superior flexibility and adaptability, such as novel molecular biological techniques and locked nucleic acid (LNA) modified probes, as well as nanotechnology-based approaches, are also included. The book also highlights the latest advances in clinical-related miRNA detection methods in living cells, circulating blood and tissue, such as in situ hybridization (ISH) and molecular imaging techniques, which are useful to elucidate the biogenesis and biological function of miRNAs in vivo. Finally, the respective advantages and drawbacks of various detection techniques in this fast-moving field are discussed, along with the challenges and promising new directions..This book offers a valuable resource for analytical chemists, biologists and physicians involved in miRNA researc | 出版日期 | Book 2015 | 关键词 | Cell imaging analysis; Electrochemical genosensors; Functional nanoprobe; MiRNA biogenesis; MiRNA detect | 版次 | 1 | doi | https://doi.org/10.1007/978-3-662-47293-4 | isbn_softcover | 978-3-662-47292-7 | isbn_ebook | 978-3-662-47293-4Series ISSN 2191-5407 Series E-ISSN 2191-5415 | issn_series | 2191-5407 | copyright | The Author(s) 2015 |
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