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Titlebook: Metronomic Chemotherapy; Pharmacology and Cli Guido Bocci,Giulio Francia Book 2014 The Editor(s) (if applicable) and The Author(s), under e

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发表于 2025-3-21 18:51:42 | 显示全部楼层 |阅读模式
书目名称Metronomic Chemotherapy
副标题Pharmacology and Cli
编辑Guido Bocci,Giulio Francia
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概述Covers all aspects of metronomic chemotherapy.Describes the pharmacological bases of metronomic chemotherapy.Presents and discusses the clinical results of all published studies on metronomic chemothe
图书封面Titlebook: Metronomic Chemotherapy; Pharmacology and Cli Guido Bocci,Giulio Francia Book 2014 The Editor(s) (if applicable) and The Author(s), under e
描述This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.
出版日期Book 2014
关键词Antiangiogenic drugs; Cancer; Metronomic chemotherapy; Pharmacology
版次1
doihttps://doi.org/10.1007/978-3-662-43604-2
isbn_softcover978-3-662-51319-4
isbn_ebook978-3-662-43604-2
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
The information of publication is updating

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发表于 2025-3-22 00:17:04 | 显示全部楼层
Book 2014preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemot
发表于 2025-3-22 04:20:43 | 显示全部楼层
Development and Evolution of the Concept of Metronomic Chemotherapy: A Personal Perspectiveetronomic chemotherapy concept is summarized along with suggestions for improving its impact as a promising means of achieving better and less toxic cancer control, not only in patients in low and middle income countries, but also patients in highly developed high income countries as well.
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Clinical Activity of Metronomic Chemotherapy in Central Nervous System Cancersma models and numerous clinical applications of metronomic regimens (e.g. etoposide, temozolomide) for adult patients with tumors of CNS have been described. Moreover, metronomic treatment may serve as a useful platform for combination strategies in certain CNS tumors.
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Metronomic Chemotherapy in Pediatric Malignanciesatriccancer. Maintenancelowdosechemotherapyhasproven itsbenefits in increasingoverallsurvival inseveral pediatric cancer. Thischapter isreviewingthecurrentknowledge ofpediatric metronomic chemotherapy and potential forfuture development ascytotoxic agents or in combinationwith targetedtherapy including its potentialapplicationinemergingcountries.
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Preclinical Activity of Metronomic Regimens with Alkylating Agents and Antimetabolitesnomic chemotherapy approach. Much of this report concerns cyclophosphamide, since, in this context, it is the most widely explored drug so far. The report also draws attention to the numerous cancer cell lines and the main murine models used.
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