书目名称 | Methods in Membrane Biology | 副标题 | Volume 10 | 编辑 | Edward D. Korn | 视频video | | 图书封面 |  | 描述 | Three articles make up Volume 10 of Methods in Membrane Biology. In the first of these, Papahadjopoulos, Poste, and Vail extensively review much of the available data on the fusion of natural membranes, model membranes (liposomes), and natural membranes with liposomes. The authors are led by their review of the experimental methods and their interpretations of the results obtained to a general theory of membrane fusion which they believe is applicable to all systems that have been studied. Arguing that although protein and carbohydrate may serve, in some cases, to bring membranes into sufficiently close proximity for fusion to occur and, in other cases, to remove peripheral and integral proteins from the regions that are to undergo fusion, the authors conclude that membrane fusion per se is solely a property of the lipid bilayer. In their view, all the experimental observations to date can be subsumed under a unifying hypothesis in which membrane fusion is the result of a phase separation in one-half of the membrane bilayer brought about by the interaction - of calcium ions with acidic phospholipids, mostly phosphatidylserine. Where half-membranes already contain sufficient acidic | 出版日期 | Book 1979 | 关键词 | Calcium; Lipid; biology; protein; proteins | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4684-0985-7 | isbn_softcover | 978-1-4684-0987-1 | isbn_ebook | 978-1-4684-0985-7 | copyright | Plenum Press, New York 1979 |
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