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Titlebook: Metals and Genetics; Bibudhendra Sarkar Book 1999 Springer Science+Business Media New York 1999 DNA.biochemistry.gene expression.genes.gen

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发表于 2025-3-21 18:38:03 | 显示全部楼层 |阅读模式
书目名称Metals and Genetics
编辑Bibudhendra Sarkar
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图书封面Titlebook: Metals and Genetics;  Bibudhendra Sarkar Book 1999 Springer Science+Business Media New York 1999 DNA.biochemistry.gene expression.genes.gen
描述During the past few years, major scientific discoveries have greatly contributed to our understanding of the relationship between metals and genetics. The fields which have contrib­ uted to this area range from Clinical Medicine and Genetics to Biochemistry and Chemistry. The aim of this book is to bring together investigators from these diverse fields to reflect on the broad implications of direct and indirect interactions of metals and genetic components. The volume begins with a tribute to the late Karen Wetterhahn, an outstanding scien­ tist in the field, who will be sadly missed by her friends and colleagues because of her un­ timely death. The book has 28 chapters contributed by scientists who are internationally known for their expertise and outstanding research. The subject matters are divided into five major sections. The first section discusses genetic response to environmental expo­ sure to metals. Potentially devastating health crises have been reported in recent years from several parts of the world, which stem from environmental exposure to metals. In this section, authors report their findings on the effects and influence of metals in gene ex­ pression and their cons
出版日期Book 1999
关键词DNA; biochemistry; gene expression; genes; genetics; molecular mechanisms; pathophysiology; physiology; regu
版次1
doihttps://doi.org/10.1007/978-1-4615-4723-5
isbn_softcover978-1-4613-7140-3
isbn_ebook978-1-4615-4723-5
copyrightSpringer Science+Business Media New York 1999
The information of publication is updating

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Reactions of Copper-Zinc Superoxide Dismutases with Hydrogen Peroxide,Copper-zinc Superoxide dismutase (CuZnSOD) is a highly abundant and ubiquitous cytosolic 32 kDa homodimeric eukaryotic enzyme that catalyzes the disproportionation of Superoxide to give dioxygen and hydrogen peroxide (reactions 1—3) (Fridovich, 1997).
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978-1-4613-7140-3Springer Science+Business Media New York 1999
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Clastogenic Effects and Influence of Inorganic Arsenic on DNA-Repair in Mammalian Systems,olize As..As inhibits DNA-repair, and our investigations on the effect of As(III) on UV-induced nucleotide excision repair in repair proficient human cells, and partly repair deficient xeroderma pigmentosum cultivated human fibroblasts indicate incision to be the most sensitive step. Inhibition occu
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Effect of Metal Compounds on the Function of Zinc Finger Proteins Involved in DNA Repair,ed from metal-treated cells, the inactivations occur at the protein level and not at the level of gene expression and/or translation of the respective DNA repair proteins. Potentially very sensitive targets for toxic metal ions are zinc finger structures in DNA binding motifs, which have been identi
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DNA Cleavage vs. Cross-Linking Using Nickel Peptides,e capable of inflicting oxidative damage on proteins and DNA (Kasprzak, 1996; Kasprzak, 1995). Both DNA strand breaks and DNA-protein cross-links have been identified as lesions resulting from exposure to excess nickel (Ciccarelli et al., 1981; Ciccarelli and Wetterhahn, 1982). Meanwhile, bioconjuga
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Copper-Dependent DNA Scission,talytically competent open-complex formed by RNA polymerase and a promoter. Finally, I would like to demonstrate that the protein targeted nuclease activity of OP-Cu provides a novel approach for investigating protein-DNA interactions.
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Modulation of Glucocorticoid Signaling and Leukocyte Activation by Transition Metals,88). MTs are classically induced by a variety of transition metals, but MTs are expressed without metal induction in many different tissues and cell types. Intriguingly, some isoforms are restricted to specific tissues. MT-3 is expressed predominantly in brain and is not metal-inducible (Uchida ..,
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