| 书目名称 | Metallocorroles for Attenuation of Atherosclerosis |
| 编辑 | Adi Haber |
| 视频video | |
| 概述 | Nominated by the Technion Israel Institute of Technology as an outstanding PhD thesis.Covers a complete study from pure chemistry through biochemical and cell culture tests to in vivo examinations.Des |
| 丛书名称 | Springer Theses |
| 图书封面 |  |
| 描述 | Adi Haber‘s thesis summarises the use of a new entity, the corrole, to combat one of the major cardiovascular diseases, atherosclerosis. She examines the effects of three rationally designed corrole-metal complexes on some of the many variables which contribute to the development of atherosclerosis. There is a focus on both the "bad" and "good" cholesterol carriers, LDL and HDL. Adi Haber proceeds from basic findings in pure chemistry through biochemical and cell culture tests to in vivo examinations. The work in this thesis shows that corroles are highly efficient both for early and late treatment of atherosclerosis in animals. These results will pave the way for ongoing regulated preclinical studies focussed on the development of metallocorroles as potential drugs for treating cardiovascular diseases. |
| 出版日期 | Book 2012 |
| 关键词 | Amphipolar Corroles; Cardiovascular Disease; Catalytic Antioxidants; Cholesterol Biosynthesis; High Dens |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-30328-9 |
| isbn_softcover | 978-3-642-44250-6 |
| isbn_ebook | 978-3-642-30328-9Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
| issn_series | 2190-5053 |
| copyright | Springer-Verlag Berlin Heidelberg 2012 |
发表于 2025-3-21 19:31:58
