Titlebook: Metal Ions in Gene Regulation; Simon Silver,William Walden Book 1998 Springer Science+Business Media Dordrecht 1998 Escherichia coli.Regul

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The Iron Responsive Element (IRE), the Iron Regulatory Protein (IRP), and Cytosolic Aconitasef organisms from bacteria to humans arises because it is an essential component of proteins that perform redox and nonredox roles in a number of cellular functions. Given that iron is one of the most abundant, chemically versatile, and reactive elements in our environment, it is not surprising that

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Menkes’ and Wilson’s Diseases: Genetic Disorders of Copper Transportamine β-hydroxylase. Copper deficiency during development can prove lethal to developing mammals, and the multiple-organ-system effects can be explained by the reduced activity of these important enzymes. The severity of copper deficiency is illustrated by the lethal X-linked genetic disorder of cop

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Yeast Metallothionein Gene Regulationage of this organism lies in the ease in which both classical and molecular genetics can be conducted, permitting the rapid identification of genes, the proteins they encode, and the functions associated with the proteins. This approach has been used highly successfully in understanding how cells ar

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The Molecular Biology of Iron and Zinc Uptake in ,mple, readily donates and accepts electrons from substrates and can display a broad range of oxidation-reduction potentials depending on the ligand environment surrounding the metal cation. Because of this unique property, iron is an important cofactor of several metalloenzymes such as ribonucleotid

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