Titlebook: Mesenchymal Stem Cells; Methods and Protocol Massimiliano Gnecchi Book 2016Latest edition Springer Science+Business Media New York 2016 Mes

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Mesenchymal Stem Cells in Cardiologyinfarction (heart attack) each year in the United States alone with roughly one-third resulting in death. There is therefore a major need for developing new and effective strategies to promote cardiac repair. Intramyocardial transplantation of mesenchymal stem cells (MSCs) has emerged as a leading c

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Mesenchymal Stem Cells in Kidney Repairney disease (CKD) in a substantial percentage of patients besides other organ dysfunctions. To date, the mortality rate per year for AKI exceeds 50 % at least in patients requiring early renal replacement therapy and is higher than the mortality for breast and prostate cancer, heart failure and diab

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Paracrine Mechanisms of Mesenchymal Stem Cells in Tissue Repaire principal mechanism underlying their therapeutic action. However, several studies have now shown that both these mechanisms are very inefficient. The low MSC engraftment rate documented in injured areas also refutes the hypothesis that MSC repair tissue damage by replacing cell loss with newly dif

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Protocols for , Differentiation of Human Mesenchymal Stem Cells into Osteogenic, Chondrogenic and Adlications for cell therapy and reparative biotechnologies. MSC have been originally isolated from the bone marrow (BM-MSC), but they have been found also in other tissues such as adipose tissue, cord blood, synovium, skeletal muscle, and lung. MSC are able to differentiate in vitro and in vivo into

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Colony Forming Unit Assaystheir wound healing properties in over 350 clinical trials worldwide. MSCs from various tissues such as adipose, bone, and others are currently being studied in clinical trials in indications for ischemic, inflammatory, autoimmune, and degenerative disorders. As a result, numerous isolation protocol

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Isolation, Culture, and Phenotypic Characterization of Mesenchymal Stromal Cells from the Amniotic Mcells to be used in cell therapy approaches due to its putative stem cell potential associated with its early embryonic origin and its immunomodulatory potential associated with its role in fetomaternal tolerance..Within the human amniotic membrane, it is possible to isolate two main cell population