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Titlebook: Membrane Dynamics and Calcium Signaling; Joachim Krebs Book 2017 Springer International Publishing AG, part of Springer Nature 2017 calciu

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Structure-Dynamic Coupling Through Ca2+-Binding Regulatory Domains of Mammalian NCX Isoform/Splice Vates become more populated in the absence of global conformational changes. Although this Ca.-dependent “population shift” is a common mechanism among NCX variants, the strength and span of backbone rigidification from the C-terminal of CBD1 to the C-terminal of CBD2 is exon dependent. The mutually
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Structural Insights into IP3R Functiono diversified extra- and intracellular stimuli remains unknown and requires high-resolution knowledge of channel molecular architecture. Recently, single-particle electron cryomicroscopy (cryo-EM) has yielded a long-awaited near-atomic resolution structure of the entire full-length type 1 IP.R. This
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Assembly of ER-PM Junctions: A Critical Determinant in the Regulation of SOCE and TRPC1s in the cytosol, ER and PM, as well as lipids in the PM. Recent studies have also suggested that SOCE and its components are compartmentalized within ER-PM junctions and that this process might require remodeling of the plasma membrane lipids and reorganization of structural and scaffolding protein
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Mitochondrial VDAC, the Na+/Ca2+ Exchanger, and the Ca2+ Uniporter in Ca2+ Dynamics and Signaling regulating mitochondrial Ca. homeostasis, oxidative phosphorylation, and Ca. crosstalk among mitochondria, cytoplasm, and the endoplasmic reticulum (ER). VDAC1 has also been recognized as a key protein in mitochondria-mediated apoptosis, and apoptosis stimuli induce overexpression of the protein in
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