Titlebook: Medical Therapy of Ulcerative Colitis; Gary R. Lichtenstein Book 2014 Springer Science+Business Media New York 2014 Antiimetabolite therap

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Tacrolimus, Sirolimus, and Mycophenolate Mofetil,osporine, especially in the long run, appears rather unfavorable. Neurological side effects such as paresthesias, nephrotoxicity, hypertension, headache, and gingival hyperplasia have been reported in up to one third of patients. As a consequence, an intense search for novel calcineurin inhibitors c

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Beyond Infliximab: Other Anti-TNF Therapies for Ulcerative Colitis,a chimeric monoclonal antibody to tumor necrosis factor-alpha (TNF-α), for Crohn’s disease (CD). However, it was not until 2005, after the results of several open-label clinical studies and of the ACT1 and ACT2 trials of IFX for treatment of moderate to severe ulcerative colitis (UC), that this agen

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ation we report that several glycogenolytic hormones exert a stimulatory effect on the rate of PRPP and purine synthesis in mouse liver in vivo (4, 5). Our studies concerning the mechanism of this phenomenon are discribed.

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Prashant R. Mudireddy M.D.,Wojciech Blonski M.D., Ph.D.,Gary R. Lichtenstein M.D., F.A.C.P., F.A.C.Gation we report that several glycogenolytic hormones exert a stimulatory effect on the rate of PRPP and purine synthesis in mouse liver in vivo (4, 5). Our studies concerning the mechanism of this phenomenon are discribed.

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Farzana Rashid M.D.,Gary R. Lichtenstein M.D., F.A.C.P., F.A.C.G., A.G.A.F.

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