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Titlebook: Medical Therapy of Ulcerative Colitis; Gary R. Lichtenstein Book 2014 Springer Science+Business Media New York 2014 Antiimetabolite therap

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The Importance of Mucosal Healing in Ulcerative Colitis,tory damage, confined exclusively to the mucosa of the colorectum, is the hallmark of the disease. The inflammation is characteristically superficial in nature and appears to begin in the rectum with variable extension to more proximal portions of the colon. This inflammation, and subsequent loss of
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Topical Mesalamine,he distal 60 cm of the colon, can be effectively treated with both oral and topical mesalamine formulations. The current 2010 American College of Gastroenterology guidelines state that for mild to moderate distal ulcerative colitis, topical mesalamine is superior to oral mesalamine or topical steroi
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Rectal Glucocorticoid Use in Ulcerative Colitis,mas have been used for over 50 years, yet experience favors topical 5-ASA as the more effective therapy. Safety issues include additional risk factors with prolonged topical corticosteroid use. Newer formulations using a first-pass metabolism feature (budesonide or beclomethasone dipropionate (BDP))
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,Azathioprine/6-Mercaptopurine Metabolism in Ulcerative Colitis: A Guide to Metabolite Assessment—Anmerica; about half have unremitting disease with symptoms of abdominal pain and diarrhea that impact patient’s quality of life and work-related productivity. It stands to reason that the major goal of therapy for physicians caring for patients with inflammatory bowel disease is to achieve and sustai
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Cyclosporine for Ulcerative Colitis,d epithelium extends continuously from the rectum and involves part or all (pancolitis) of the colon. Symptomatically, patients exhibit increased, bloody, bowel movements with fecal urgency, diarrhea, abdominal cramping, abdominal pain, hematochezia, and fever. These characteristics can have a gradu
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