Titlebook: Mechanism of Action; David Gottlieb (Professor of Plant Pathology),Paul Book 1967 Springer-Verlag Berlin · Heidelberg 1967 Chloramphenicol

brachytherapy

书目名称Mechanism of Action影响因子(影响力)




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Offbeat

Pyocyanine,ase. Later investigations, however, showed that several factors were present, none of which had enzymatic activity, and that the major active principle was pyocyanine. The isolation and chemical nature of pyocyanine has been described by S. (1941) and the structure was elucidated by W. and S. (1924, 1929) and H. (1938).

Minikin

Pluramycin,) observed that a macromolecular antitumor substance (molecular weight 30, 000–60, 000) is also produced by the same organism. It consists of a pluramycin-like prosthetic group and a glycoprotein, and is designated plurallin.

ADORE

Daunomycin and Related Antibiotics, Daunomycin is closely related to the anthracyclines. Following B. suggestion (4963), those antibiotics that contained a tetrahydrotetracenquinone chromophore linked to a sugar should all be included in the anthracycline group. The chromophores of such antibiotics have different substituents on the nucleus (Fig. 1 and Table 1).

Instrumental

s to keep abreast of the literature. Gone were the years when we were able to keep a biblio­ graphy on antibiotics and feel confident that we could find everything that was being published on this subject. These fields of investigation were moving for­ ward so rapidly and were encompassing so wide a

BOOM

Penicillins and Cephalosporins, effects may be dominant and of the greatest significance while a biochemically minded individual will wish to know the nature of specific metabolic changes; a clinician interested in infectious diseases wishes to know what events are observable in the host and how these relate to the probable success or failure of his therapy.

相互影响

bypass

惰性气体

Griseofulvin,y of “curling factor” with griseofulvin was determined chemically by GROVE and MCGOWAN (1947), and biologically by B... (1949). Subsequent studies have demonstrated that . and . also produce the antibiotic (B..., 1949, 1955). The griseofulvin analogs, bromogriseofulvin and dechlorogriseofulvin have also been isolated from fungi (M., 1951, 1954).

Enteropathic

Chromomycin, Olivomycin and Mithramycin,tics is similar, but not identical; there are also some differences in the toxicity and pharmacology of these products, which have been compared in a recent review (G., 1965). Biochemical mechanisms of action of these antibiotics have much in common.