书目名称 | Mathematical Modeling of Mitochondrial Swelling | 编辑 | Messoud Efendiev | 视频video | | 概述 | Presents new mathematical models of mitochondrial swelling that take into account, for the first time, the spatial effects.Proves both the well-posedness of the models under consideration and extensiv | 图书封面 |  | 描述 | .The mathematical models considered in this book can help to understand the swelling of mitochondria. For the first time, it presents new mathematical models of mitochondrial swelling that take into account, in particular, spatial effects. The results presented here could make it possible to predict properties of the underlying biological mechanisms. Taking into account that mitochondria could move within a cell, lead to a PDE-PDE model. The book discusses the well-posedness and long-term dynamics of solutions, depending on boundary conditions reflecting the in vitro and in vivo cases. These analytical and numerical results have inspired colleagues from the Institute of Pharmacology and Toxicology of the Helmholtz Center Munich to design new experiments justifying the theoretical and numerical results that are obtained. The book is intended for graduates students and researchers with a solid mathematical background and an interest in cell biology.. | 出版日期 | Book 2018 | 关键词 | 35B40 35K45 37N25; swollen mitochondria; calcium evolution; apoptosis; boundary conditions; spreading cal | 版次 | 1 | doi | https://doi.org/10.1007/978-3-319-99100-9 | isbn_softcover | 978-3-030-07567-5 | isbn_ebook | 978-3-319-99100-9 | copyright | Springer Nature Switzerland AG 2018 |
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