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Titlebook: Mathematical Descriptors of Molecules and Biomolecules; Applications in Chem Subhash C. Basak Book 2025 The Editor(s) (if applicable) and T

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Marjan Vračko,Subhash C. Basakgic challenge studies, postmortem analyses and a recent sufficiently powered genome-wide association study and copy number variant studies provide compelling evidence that NMDA receptor hypofunction is an important pathophsysiologic feature of schizophrenia. Silencing the gene encoding serine racema
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Ramanathan Natarajan,Subhash C. Basak,Claudiu N. Lungu accumulation, nuclear translocation of the mitochondria protein AIF, and large-scale DNA cleavage. Understanding the mechanisms and interactions of cell death signaling will not only help to develop neuroprotective strategies to halt neurodegeneration, but also provide biomarkers for monitoring dis
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Denis Sabirov,Alexandra Zimina,Igor Shepelevichgions, in large international consortia with sufficient number of cases and controls. The four largest LOAD GWAS consortia joined forces forming a mega-consortium known as the International Genomics of Alzheimer’s Project (IGAP) and conducted a mega-meta-analysis of 25,500 LOAD cases and 48,500 unaf
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Ziyun Zhou,Lorenza Pacini,Laurent Vuillon,Claire Lesieur,Guang Huwill offer the biomedical sciences new insight for the study of neurodegenerative diseases, multifactorial complex, and rare diseases. In this chapter, an overview of the current genetic and epigenetic progresses in AD, FTD, PD, and ALS, reached by the application of the new genetic technologies, wi
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Book 2025 biodescriptors. Currently there is a steady increase in the use of data analytics and model-based decision support systems in basic and applied research in chemoinformatics, bioinformatics, pharmaceutical drug design, predictive toxicology, and computational biology.  Since there are a plethora of
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