书目名称 | Mapping Genetic Interactions | 编辑 | Franco Joseph Vizeacoumar,Andrew Freywald | 视频video | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible result.Contains key notes and implementation advice from the experts | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .This volume details methods of identifying synthetic lethal, genetic interactions by various approaches in different model systems including human cancer cells. Chapters guide readers through genetic interactions in model organisms, RNA interference, CRISPR/Cas9 based genome editing technologies, drug-gene interactions, mapping chemical genetic interactions, synergistic drug-gene relations, single cell sequencing, gene expression profiling, and novel genetic interactions. Written in the format of the highly successful .Methods in Molecular Biology .series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols... ..Authoritative and cutting-edge, .Genetic Interaction Mapping .aims to be a useful practical guide to researches to help further their study in this field.. | 出版日期 | Book 2021 | 关键词 | lower eukaryotes; synthetic genetic array (SGA); ; D; melanogaster; C; elegans; CRISPR | 版次 | 1 | doi | https://doi.org/10.1007/978-1-0716-1740-3 | isbn_softcover | 978-1-0716-1742-7 | isbn_ebook | 978-1-0716-1740-3Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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