Titlebook: Managing Complexity, Reducing Perplexity; Modeling Biological Marcello Delitala,Giulia Ajmone Marsan Conference proceedings 2014 Springer

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Homing to the Niche: A Mathematical Model Describing the Chemotactic Migration of Hematopoietic SteIn this contribution, a quantitative model for this process is presented. The model consists of chemotaxis equations coupled with an ordinary differential equation on the boundary of the domain and subjected to nonlinear boundary conditions. The existence and uniqueness of a local solution is proved

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DDE Models of the Glucose-Insulin System: A Useful Tool for the Artificial Pancreas,der investigation more accurately, without the use of auxiliary fictitious compartments. This work deals with Delay Differential Equation (DDE) models exploited in the specific framework of the glucose-insulin regulatory system, and a brief review of the DDE models available in the literature is pre

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Quantitative Approaches to Heterogeneity and Growth Variability in Cell Populations,dvances, both theoretical and experimental, in quantification and modeling of the clonal variability of proliferation rates within cell populations. Our aim is to highlight a few stimulating examples from this fledgling and exciting field, in order to frame the issue and point to challenges and oppo

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Some Thoughts on the Ontogenesis in B-Cell Immune Networks,lf-antigen are not assumed as purely random objects, which is a too strong simplification, but rather they are extracted from a biased probability distribution, mature lymphocytes displaying a higher weighted connectivity are also more affine with the set of self-antigens, ultimately conferring stro

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