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Titlebook: Lysosomes; Paul Saftig Book 2005 Springer-Verlag US 2005 Chaperone.Organelle.Resorption.enzymes.proteins

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发表于 2025-3-21 19:22:01 | 显示全部楼层 |阅读模式
书目名称Lysosomes
编辑Paul Saftig
视频videohttp://file.papertrans.cn/590/589250/589250.mp4
概述Most up-to-date and comprehensive volume on lysosomal storage diseases available.Chapters written by leading experts in the field.Features chapters summaries and detailed illustrations
丛书名称Medical Intelligence Unit
图书封面Titlebook: Lysosomes;  Paul Saftig Book 2005 Springer-Verlag US 2005 Chaperone.Organelle.Resorption.enzymes.proteins
描述.Lysosomes are membrane-surrounded organelles which are present in all animal cells. The importance of this organelle is underlined by an increasing number of human diseases, which are associated with an impaired function of the lysosomal compartment...This book summarizes the current state-of-the art knowledge about this unique organelle. It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal storage disorders, and new concepts on how to treat these diseases. In addition to these classical topics, new insights into lysosomal functions are covered by chapters dealing with specialized lysosomes involved in bone resorption and plasma membrane repair, the lysosomal transciptome, and proteome and the emerging role of lysosomes in special forms of autophagy...This book will provide readers with a comprehensive overview into how this fascinating organelle works and how research in the field is developing. .
出版日期Book 2005
关键词Chaperone; Organelle; Resorption; enzymes; proteins
版次1
doihttps://doi.org/10.1007/0-387-28957-7
isbn_softcover978-1-4419-3804-6
isbn_ebook978-0-387-28957-1
copyrightSpringer-Verlag US 2005
The information of publication is updating

书目名称Lysosomes影响因子(影响力)




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书目名称Lysosomes网络公开度学科排名




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书目名称Lysosomes读者反馈学科排名




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发表于 2025-3-21 23:44:50 | 显示全部楼层
Transport of Lysosomal Enzymes,n identified. The hydrolases are enclosed by a membrane containing a set of highly glycosylated lysosomal membrane proteins. Lysosomal enzymes are also components of cell type-specific compartments referred to as lysosome-related organelles which include melanosomes, lytic gran-ules, MHC class II co
发表于 2025-3-22 04:04:35 | 显示全部楼层
Adaptor Proteins in Lysosomal Biogenesis,sicles which bud from the donor compartment and are transported to and fuse with the proper acceptor compartment. The proteins forming the vesicle-coat bind to the cytoplasmic domains of the cargo proteins and recruit additional proteins like clathrin to the site of vesicle formation. These proteins
发表于 2025-3-22 06:03:12 | 显示全部楼层
Lysosomal Membrane Proteins,of fusion events beween lysosomes and other organelles, and transport of degradation products to the cytoplasm. Lysosomal membrane proteins are usually highly glycosylated proteins decorating the luminal surface of lysosomal membranes. LAMP-1, LAMP-2 and LIMP-2 are the most abundant components of th
发表于 2025-3-22 12:42:32 | 显示全部楼层
Lysosomal Proteases,issue- or cell type-specific manner. Although we still call them lysosomal proteases, the enzymes are usually detected within all vesicles of the endocytic pathway. In specific cell types, they might even become secreted and might fulfill important tasks in the direct pericellular surrounding. Funct
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发表于 2025-3-22 22:10:14 | 显示全部楼层
Cholesterol Transport in Lysosomes,has many possible fates within the cell, including incorporation into membranes, metabolic conversion to a number of different products, covalent modification of specific proteins, regulation of gene expression, and efflux from the cell. Distinct trafficking pathways are thought to exist for de novo
发表于 2025-3-23 01:49:18 | 显示全部楼层
Therapy of Lysosomal Storage Diseases,r macromolecules to low molecular components that are transported to the cytoplasm for reutilization in the biosynthetic pathways of the cell. Up to now more than 50 different lysosomal hydrolases catalyzing the degradation of proteins, lipids, nucleic acids and carbohydrates have been identified. T
发表于 2025-3-23 06:43:58 | 显示全部楼层
Lysosomal Proteome and Transcriptome,nd others in the 1950s. Nevertheless, a lot of questions are still open, and some of them can be addressed using screening techniques. Among them are questions about the structure of the lysosomal mem-brane, the function of its proteins, and the effect of lysosomal dysfunction on cell functions. Alt
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