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Titlebook: Lung Stem Cells in the Epithelium and Vasculature; Amy Firth,Jason X.-J. Yuan Book 2015 Springer International Publishing Switzerland 2015

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发表于 2025-3-21 17:17:24 | 显示全部楼层 |阅读模式
书目名称Lung Stem Cells in the Epithelium and Vasculature
编辑Amy Firth,Jason X.-J. Yuan
视频video
概述Stem and progenitor cells of the lung are a rapidly developing area of research interest.Comprehensive coverage of stem cells in endothelium and vasculature from development through disease and repair
丛书名称Stem Cell Biology and Regenerative Medicine
图书封面Titlebook: Lung Stem Cells in the Epithelium and Vasculature;  Amy Firth,Jason X.-J. Yuan Book 2015 Springer International Publishing Switzerland 2015
描述.This book covers the identification and role of endogenous lung stem cells in health and disease, particularly the most recent advances. In addition, it discusses the rapidly growing field of stem cells and cell therapy as it relates to lung biology and disease as well as .ex vivo .lung bioengineering. Such approaches may provide novel therapeutic approaches for lung diseases. Human pluripotent stem cell differentiation to model the pulmonary epithelium and vasculature is also discussed..World-recognized scientists who specialize in studying both the lung epithelium and pulmonary vasculature contribute the chapters. Topics covered include: stem cell niches in the lung, the role of progenitor cells in fibrosis and asthma, iPSC in modeling lung disease, vascular repair by endothelial progenitor cells and circulating fibrocytes in pulmonary vascular remodeling. This volume of the .Stem Cell Biology and Regenerative Medicine. series is essential reading for researchers and clinicians interested in stem cells, lung biology and regenerative medicine. It is also an invaluable resource for advanced students studying cell biology, regenerative medicine and lung physiology..
出版日期Book 2015
关键词Clara cells; Progenitor cells; Pulmonary hypertension; Stem cells; Vascular remodeling
版次1
doihttps://doi.org/10.1007/978-3-319-16232-4
isbn_softcover978-3-319-35338-8
isbn_ebook978-3-319-16232-4Series ISSN 2196-8985 Series E-ISSN 2196-8993
issn_series 2196-8985
copyrightSpringer International Publishing Switzerland 2015
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发表于 2025-3-21 20:59:54 | 显示全部楼层
Type II Cells as Progenitors in Alveolar Repairal roles in mediating the gas exchange. Cuboidal type II cells occupy only 5 % of the area but have multiple functions including secreting surfactant, transporting ion and fluid, and modulating immunity. Type II cells also function as progenitor cells by self-renewal and differentiating into type I
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发表于 2025-3-22 08:38:17 | 显示全部楼层
Bronchioalveolar Stem Cells in Cancerfollowing injury, and in regeneration following tissue loss. In the highly branched and compartmentalized lung, homeostatic maintenance and responses to injury are driven by multiple, different, resident stem/progenitor cell populations. Consistent or repeated failure of lung stem/progenitor cell fu
发表于 2025-3-22 12:07:36 | 显示全部楼层
Role of Progenitors in Pulmonary Fibrosis and Asthmanges that impair lung function. Lung injury elicits the recruitment of stem cells and other progenitor cells and fibrocytes to the airways. These cells proliferate and differentiate into fibroblasts and myofibrolasts that secrete collagen and other extracellular matrix components that damage the nor
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Challenges of Cell Therapy for Lung Diseases and Critical Illnesseseen increasing in the past decades. Moreover, the currently available treatments are not able to reverse the pathological damage or to restore normal organ function. Thus, there is an urgent search for new regenerative strategies. In parallel, while advances in supportive care have improved survival
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The Hope for iPSC in Lung Stem Cell Therapy and Disease Modelingly difficult; iPSC provide the potential for the generation of reproducible systems for investigating the cellular, molecular, and genetic mechanisms that lead to the development and pathogenesis of human lung disease. In the future, this technology holds great potential for the development of novel
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Ex Vivo Lung Bioengineeringe therapeutic option. However, the number of suitable donor lungs is inadequate to meet current clinical demands and thus alternative options are desperately needed. There are a number of conceptually viable alternatives for generating functional pulmonary tissue ex vivo, including the use of either
发表于 2025-3-23 01:43:47 | 显示全部楼层
Endothelial Colony-Forming Cells in Pulmonary Arterial Hypertensionnd led to the discovery of a subset of cells with robust endothelial regenerative capacity. These so-called endothelial colony-forming cells (ECFCs) are phenotypically identical to cultured endothelial cells, but exhibit high proliferative potential, capacity for self-regeneration, and in vivo vascu
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Mesothelial Progenitors in Development, Lung Homeostasis, and Tissue Repairetic tools, lineage properties, and signals controlling migration and differentiation. We also discuss the potential role of this cell in endogenous injury responses, inflammation, fibrosis, and tissue regeneration.
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