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Titlebook: Lipoxygenases in Inflammation; Dieter Steinhilber Book 2016 Springer International Publishing Switzerland 2016 allergic and cardiovascular

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发表于 2025-3-21 16:09:05 | 显示全部楼层 |阅读模式
书目名称Lipoxygenases in Inflammation
编辑Dieter Steinhilber
视频video
概述Summarizes the functions of lipoxygenases in health and inflammatory diseases.Gives a comprehensive account of the role of lipoxygenase metabolites in pathophysiology.Chapters cover role in diseases,
丛书名称Progress in Inflammation Research
图书封面Titlebook: Lipoxygenases in Inflammation;  Dieter Steinhilber Book 2016 Springer International Publishing Switzerland 2016 allergic and cardiovascular
描述Oxidation of polyunsaturated fatty acids by lipoxygenases leads to a variety of fatty acid metabolites which play important roles in physiology but also in pathophysiology. Data accumulated during the last decade point to the fact that lipoxygenase metabolites are involved in host defence reactions, cardiovascular system and contribute to the development of inflammatory and allergic diseases, cardiovascular disease and cancer. This PIR volume summarizes the physiological and pathophysiological functions of lipoxygenases.
出版日期Book 2016
关键词allergic and cardiovascular diseases; fatty acid metabolites; inflammation; leukotrienes; lipoxygenases;
版次1
doihttps://doi.org/10.1007/978-3-319-27766-0
isbn_softcover978-3-319-80212-1
isbn_ebook978-3-319-27766-0Series ISSN 1422-7746 Series E-ISSN 2296-4525
issn_series 1422-7746
copyrightSpringer International Publishing Switzerland 2016
The information of publication is updating

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发表于 2025-3-21 23:51:51 | 显示全部楼层
Lipoxygenases and Cardiovascular Diseases,th lipoxins and peptide agonists, and in murine models of atherosclerosis, FPR2/ALX deletion decreases atherosclerotic lesion size but increases atherosclerotic plaque instability. Finally, omega-3 essential fatty acids may serve as substrate for the LO enzymes yielding mediators that promote inflam
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5-Oxo-ETE and Inflammation,as it promotes the survival and proliferation of a number of cancer cell lines and rescues these cells from apoptosis induced by inhibitors of the 5-LO pathway. OXE receptor antagonists, which are currently under development, may be useful therapeutic agents in asthma and other eosinophilic disorder
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J. Roos,B. Kühn,J. Fettel,I. V. Maucher,M. Ruthardt,A. Kahnt,T. Vorup-Jensen,C. Matrone,D. Steinhilb developing model systems to aid our understanding of the complex activities of the individual plant. Soil chemists are examining the interactions between iron and various minerals and organic matter soil components in the root zone. Microbiologists are providing a crucial perspective on how the int
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