| 书目名称 | Liposomes | | 副标题 | Methods and Protocol | | 编辑 | Volkmar Weissig | | 视频video | http://file.papertrans.cn/587/586918/586918.mp4 | | 概述 | Volume 2 specifically:.Provides an essential and comprehensive source for every investigator whose research involves any one aspect of lipids as essential components of biological membranes.Serves as | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | Efforts to describe and model the molecular structure of biological membranes go back to the beginning of the last century. In 1917, Langmuir described membranes as a layer of lipids one molecule thick [1]. Eight years later, Gorter and Grendel concluded from their studies that “the phospholipid molecules that formed the cell membrane were arranged in two layers to form a lipid bilayer” [2]. Danielli and Robertson proposed, in 1935, a model in which the bilayer of lipids is sequestered between two monolayers of unfolded proteins [3], and the currently still accepted fuid mosaic model was proposed by Singer and Nicolson in 1972 [4]. Among those landmarks of biomembrane history, a serendipitous observation made by Alex Bangham during the early 1960s deserves undoubtedly a special place. His fnding that exposure of dry phospholipids to an excess of water gives rise to lamellar structures [5] has opened versatile experimental access to studying the biophysics and biochemistry of biological phospholipid membranes. Although during the following 4 decades biological membrane models have grown in complexity and functionality [6], liposomes are, besides supported bilayers, membrane nanodisc | | 出版日期 | Book 2010 | | 关键词 | Biochemistry; Biological membranes; Biophysics; Cholestrol; FRET; Glycolipids; Lipids; Phospholipids; biosyn | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-60761-447-0 | | isbn_softcover | 978-1-61779-687-6 | | isbn_ebook | 978-1-60761-447-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 2010 |
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