书目名称 | Leukemia | 副标题 | Methods and Protocol | 编辑 | Chi Wai Eric So | 视频video | | 概述 | An easily accessible reference volume for the latest diagnostic and research techniques for studying hematological malignances as written by leading researchers in the field.Systematic and reliable mo | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .Recent advances in molecular and cellular biology techniques have significantly improved our ability to detect, monitor, model and study the underlying molecular basis and pathogenesis of leukemia, yet we are still in an early discovery stage and much more work is needed in order to develop better strategies to diagnose, classify and treat this biologically and clinically diverse disease. In .Leukemia: Methods and Protocols., expert researchers bring together a wide range of state-of-the-art laboratory methods and detailed protocols that are useful for both clinical and basic research scientists working on the disease. The volume provides techniques for prenatal backtracking of leukemic clone, molecular diagnosis, detection of genome-wide genetic abnormalities and profiling, identification of unknown fusion genes, monitoring of minimal residual diseases, disease modeling using murine and human primary hematopoietic cells, studying of normal and malignant hematopoiesis, identification of interacting partners with leukemia associated oncoproteins, and global characterization of genome-wide epigenetic changes in leukemic cells. Written in the highly successful .Methods in Molecular B | 出版日期 | Book 2009 | 关键词 | Anti-cancer therapy; Disease modeling; Experimental hematology; Hematological malignancies; Laboratory; M | 版次 | 1 | doi | https://doi.org/10.1007/978-1-59745-418-6 | isbn_softcover | 978-1-4939-5630-2 | isbn_ebook | 978-1-59745-418-6Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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