Titlebook: LC-MS in Drug Bioanalysis; Q. Alan Xu,Timothy L. Madden Book 2012 Springer Science+Business Media, LLC 2012 Bioanalysis.LC-MS.LC-MS/MS.Liq

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Therapeutic Drug Monitoring to Support Clinical Pharmacogenomics,b-therapeutic. TDM can also improve efficacy for tamoxifen for patients taking drug inhibitors, and be useful for determining the mechanism of clopidogrel resistance (i.e., pharmacokinetics vs. pharmacodynamics). Since there are no specific immunoassays for these drugs and metabolites for serum meas

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The Analysis of Antipsychotic Drugs in Human Biosamples by LC-MS, This chapter reviews published multianalyte methods and highlights the important ­criteria when developing an analytical method for the detection of APs, potential pitfalls, and the importance of appropriate method validation, in order to assure reproducibility of results.

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Therapeutic Drug Monitoring of Targeted Anticancer Therapy. Tyrosine Kinase Inhibitors and Selectivapeutic Drug Monitoring (TDM) approach, whereby the careful selection of TKI dosage is adapted to each patient according to individual plasma levels, contributing to minimize the risk of major adverse reactions and to increase the probability of efficient, long-lasting, therapeutic response. This ch

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for printed text, and styles for handwritten text bring new difficulties for segmentation and recognition algorithms..This chapter contains descriptions of some methodologies, presented from recent research, that propose solutions that overcome these obstacles. Line segmentation solutions include h

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Min Meng Ph.D.,Patrick K. Bennettter recognition (OCR) and information retrieval technology. Considering the global upsurge of so-called minor and/or unknown languages, it has become a technological challenge to develop automatic or semiautomatic systems that can identify a language vis-à-vis a script in which a particular piece of