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Titlebook: Innovative Designs and Analyses for Small Population Clinical Trials; Development Strategi Jingjing Ye,Lei Nie Book 2024 The Editor(s) (if

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Modelling and Simulations, systems. This paper explores the fundamental concepts, methods, and applications of modeling and simulation in drug development for rare diseases. At its core, modeling involves constructing simplified representations of real-world phenomena, while simulation involves executing these models to obse
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Operation and Other Considerations,o enriched the possible data collection methods via digital health technologies (DHTs) and integration of siloed data generated through various sources. In the chapter, we first discuss the requirement and validations for use of the DHTs in the regulatory setting. Various emerging practical consider
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Jingjing Ye,Lei Niets, it gives clear guidance based on the fundamental principles of moral philosophy, explaining them in simple language and illustrating them with abundant clinical examples and case studies. The strength of this text is in its emphasis on normative ethics and critical thinking, and that there is tr
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Jingjing Ye,Lei Nieto set up those committees is linked to an analysis of ethical aspects in medical research projects as published in an American medical journal of high reputation. The results prompted the National Instituts of Health (NIH) to require an assessment of research projects by an Institutional Review Boa
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