| 书目名称 | Ion Channels | | 编辑 | Toshio Narahashi | | 视频video | | | 丛书名称 | Ion Channels | | 图书封面 |  | | 描述 | In the past few years, the scientific community has witnessed rapid and significant progress in the study of ion channels. Technological advance ment in biophysics, molecular biology, and immunology has been greatly accelerated, making it possible to conduct experiments that were deemed very difficult if not impossible in the past. For example, patch-clamp tech niques can now be used to measure ionic currents generated by almost any type of cell, thereby allowing us to analyze single-channel events. It is now possible to incorporate purified ion channel components into lipid bilayers to reconstitute an "excitable membrane." Gene cloning and monoclonal antibody techniques provide us with new approaches to the study of the molecular structure of ion channels. A variety of drugs have now been found or are suspected to interact with ion channels to exert therapeutic effects. In addition to the classical exam ples, as represented by local anesthetics, many other drugs, including cal cium antagonists, psychoactive drugs, cardiac drugs, and anticonvulsants, have been shown to alter the ion channel function. For certain pesticides such as pyrethroids and DDT, sodium channels are clearl | | 出版日期 | Book 1990 | | 关键词 | ATP; Calcium; Lipid; Nucleotide; Peptide; biology; biophysics; kinetics; molecular biology; primary structure | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4615-7305-0 | | isbn_ebook | 978-1-4615-7305-0 | | copyright | Springer-Verlag US 1990 |
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发表于 2025-3-21 18:29:18
