Titlebook: Interdisciplinary Approaches to Gene Therapy; Legal, Ethical and S Stefan Müller,Jürgen W. Simon,Jan W. Vesting Book 1997 Springer-Verlag B

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Safety Considerations in Construction of Viral Vectors for Gene Therapy still in its infancy, but also since it is unlikely that a single method of gene transfer will be applicable to the broad range of clinical situations which has to be dealt with, e.g. in targeting the various different tissues in the human body.

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Gene Therapy of Human Melanoma — from Animal Experiments to the Clinical Trialis human ICAM 1 was not sufficient enough to prevent growth of parental tumour cells. In the preclinical studies B78H1 murine melanoma cells were stable transfected with cDNAs coding for human IL6, murine sIL6R (soluble IL6 receptor) and human leukaemia inhibitory factor (LIF). The parental and tran

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The Regulation of Genetic Technology in the United Kingdom: Hard or Soft Options?ill often recommend that action be taken to address the original concerns. Therefore stage four tends to see the government presented with a variety of options. It can choose to ignore the report and take no action, an attractive option if the level of public interest has diminished. Alternately, th

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Regulation of Genetic Therapy - The American Experiencean subjects. The local board has the opportunity to oversee the individual investigator and the equity of the protocol for the individual human subject. Gene therapy protocols in the US should have IRB review before they are sent to the national level for evaluation.