Titlebook: Inflammatory Mechanisms in Mediating Hearing Loss; Vickram Ramkumar,Leonard P. Rybak Book 2018 Springer International Publishing AG, part

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The Contribution of Anti-oxidant and Anti-inflammatory Functions of Adenosine A1 Receptor in Mediaton to the affected tissue. This action is mediated by adenosine receptors (ARs) which are ubiquitously expressed on the surface of cells which respond to the elevation in levels of adenosine in the extracellular fluid. While endogenous adenosine released to the extracellular fluid could confer prote

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Trauma, Inflammation, Cochlear Implantation Induced Hearing Loss and Otoprotective Strategies to Lig to hair cell death and hearing impairment. In this chapter we discuss the most recent literature regarding signaling pathways of hair cell loss, mechanisms and inflammatory responses after noise exposure and electrode insertion, and otoprotective strategies that can limit hair cell death and heari

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Implementation and Outcomes of Clinical Trials in Immune-Mediated Hearing Loss and Other Rare Diseaof new drugs to treat these orphan diseases. Autoimmune inner ear disease, and related diseases of immune mediated hearing loss are yet to be classified orphan diseases. In this chapter, we have addressed some of the unique challenges in designing clinical trials for Autoimmune Inner Ear Disease, Su

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Douglas E. Vetter,Kathleen T. Yeeto its maximum and minimum limits. A digital filter is subject to saturation if it is implemented in a finite word length format. Saturation nonlinearities are also purposely introduced into engineering systems such as control sys­ tems and neural network systems. Regardless of how saturation arises

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