Titlebook: Inflammation: Mechanisms and Treatment; Proceedings of the F D. A. Willoughby (Professor),J. P. Giroud (Profess Conference proceedings 1980

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Review of pathogenesis of adjuvant arthritis and its relation to rheumatoid arthritis (Abstract)ems to be the best available model of human inflammatory joint diseases. In addition to the usual technique of inducing this disease in rats by complete Freund’s adjuvant it has recently been observed that a similar type of polyarthritis can be induced in rats with incomplete Freund’s adjuvant (IFA)

Patrimony

The anti-inflammatory activity of aspirin: the active metabolite interference with the biosynthesis of prostaglandins. The basis of the idea was the finding that aspirin could inhibit the activity of the so-called prostaglandin synthetase enzyme system under . conditions. The hypothesis has been restated in later years in a more explicit fashion. Thus, Gryglewsk

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Indomethacin-sodium salicylate combination/RGH-6705 as a new possibility in the treatment of inflammnished. The antagonism of ulceration of stomach and intestines could be optimalized using a certain indomethacin-sodium salicylate ratio. In human studies, gastrointestinal blood loss provoked by indomethacin was significantly reduced by concomitant dosage of sodium salicylate, show by .Cr-labelled

Magnificent

Tropesin: a new potential anti-rheumatic ester of indometacinlatively high toxicity on the other hand, have initiated several working teams to search for derivatives of indometacin with more advantageous therapeutic properties. In the course of many years a great variety of analogues of indometacin have been synthesized, and esters doubtlessly belong among th

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Review of pathogenesis of adjuvant arthritis and its relation to rheumatoid arthritis (Abstract)ted in traditional adjuvant arthritis. This animal disease can be inhibited or minimized by the early administration of immunosuppressive agents, or antiviral agents such as interferon. Later modifications of these forms of arthritis occur when anti-inflammatory compounds such as corticosteroids, bu

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