| 书目名称 | Inflammation and Metastasis | | 编辑 | Yoshiro Maru | | 视频video | | | 概述 | Offers new concepts of inflammation such as homeostatic inflammation, which helps to give new insights into the understanding of metastasis.Reinforces understanding of inflammation with full step-by-s | | 图书封面 |  | | 描述 | .This book provides the latest information on cancer metastasis from the standpoint of inflammation, especially innate immune reactions caused by endogenous mediators but not exogenous pathogens, with ideas on how to understand the complicated mechanisms of metastasis as well as to interpret therapeutic targets. The book includes the topic of the emerging roles of endogenous TLR4 ligands whose functions are shared intriguingly by metastasis and auto-inflammatory diseases such as rheumatoid arthritis. For example, most cancer therapies established so far are effective initially. However, they eventually face the great obstacles of drug resistance, immune evasion, and metastatic progression. One of the endogenous TLR4 ligands is thought to contribute to all three processes. The most important features of the book are to explain a concept of homeostatic inflammation, disturbance of which in the lungs gives rise to the establishment of a pre-metastatic pulmonary microenvironment based onprimary tumor-mediated hijacking of the innate immune defense system against respiratory infection. In addition, structure-based thinking is another important feature of this book. It is proposed that i | | 出版日期 | Book 2016 | | 关键词 | Inflammation; Metastasis; Leukocytes; Microenvironment; Pathogen sensors; Immune system; Coagulation; Angio | | 版次 | 1 | | doi | https://doi.org/10.1007/978-4-431-56024-1 | | isbn_softcover | 978-4-431-56756-1 | | isbn_ebook | 978-4-431-56024-1 | | copyright | Springer Japan 2016 |
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发表于 2025-3-21 18:59:31
