Titlebook: Inflammasome Signaling and Bacterial Infections; Book 2016

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Inflammasome Recognition and Regulation of the , Flagellum,lagellin and pathogen–host interactions are controlled by a complex stationary phase regulatory network, detecting nutrient availability as well as the . quorum sensing (Lqs) signaling compound LAI-1 (3-hydroxypentadecane-4-one). Thus, the small molecule LAI-1 coordinates . . flagellin production an

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Role of Canonical and Non-canonical Inflammasomes During , Infection,es macrophage microbicidal functions and primes for caspase-11 expression. In contrast, during melioidosis, IL-1β has deleterious effects due to excessive recruitment of neutrophils to the lung and consequent tissue damage.

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,, Inflammasomes: Integrated Responses to a Cytosolic Stealth Bacterium, hiding strategy of . to escape recognition by innate sensors and to resist to bacteriolysis in the host cytosol. Finally, we discuss the inability of the inflammasome sensors to detect . subspecies . strains, making them highly pathogenic stealth microbes.

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