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Titlebook: Individualized Medicine; Ethical, Economical Tobias Fischer,Martin Langanke,Susanne Michl Book 2015 Springer International Publishing Swit

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发表于 2025-3-21 17:28:33 | 显示全部楼层 |阅读模式
书目名称Individualized Medicine
副标题Ethical, Economical
编辑Tobias Fischer,Martin Langanke,Susanne Michl
视频video
概述A comprehensive and well-grounded outline of Individualized Medicine.Presentation and assessment of concrete examples based on multi-year research.Intensive discussion of barriers for translation conc
丛书名称Advances in Predictive, Preventive and Personalised Medicine
图书封面Titlebook: Individualized Medicine; Ethical, Economical  Tobias Fischer,Martin Langanke,Susanne Michl Book 2015 Springer International Publishing Swit
描述In 2009 the University Medicine Greifswald launched the “Greifswald Approach to Individualized Medicine” (GANI_MED) to implement biomarker-based individualized diagnostic and therapeutic strategies in clinical settings. Individualized Medicine (IM) has led not only to controversies about its potentials, but also about its societal, ethical and health economic implications. This anthology focusses on these areas and includes – next to clinical examples illustrating how the integrated analysis of biomarkers leads to significant improvement of therapeutic outcomes for a subgroup of patients – chapters about the definition, history and epistemology of IM. Additionally there is a focus on conceptual philosophical questions as well as challenges for applied research ethics (informed consent process, the IT-based consent management and the handling of incidental findings). Finally it pays attention to health economic aspects. The possibilities of IM to initiate a paradigm shift in the Germanhealth care provision are investigated. Furthermore, it is asked whether the G-DRG system is ready for the implementation of such approaches into clinical routine.
出版日期Book 2015
关键词Biomarkers; Health Economics; Individualized Medicine; Personalised Medicine; Research Ethics
版次1
doihttps://doi.org/10.1007/978-3-319-11719-5
isbn_softcover978-3-319-34698-4
isbn_ebook978-3-319-11719-5Series ISSN 2211-3495 Series E-ISSN 2211-3509
issn_series 2211-3495
copyrightSpringer International Publishing Switzerland 2015
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发表于 2025-3-21 22:30:14 | 显示全部楼层
The Meaning of “Individualized Medicine”: A Terminological Adjustment of a Perplexing Termnalysis of relevant explanations and definitions from English and German speaking areas. It secondly presents a definition according to which the term “Individualized Medicine” should be used for describing research approaches and health care practices, when the biomarker-based prediction of (a) dis
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Individualized Medicine Within the GANI_MED Projectajor challenges of Individualized Medicine. The major goals of Individualized Medicine require excellent clinical stratification of patients as well as the availability of genomic data and biomarkers as prerequisites for the development of novel diagnostic tools and therapeutic strategies. In this c
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The Epistemics of “Personalized Medicine”. Rebranding Pharmacogeneticsyzes the intellectual formation of pharmacogenetic, -genomics as a disciplinary field. It explores when, how, and why the leading journals in the field present themselves as part of the overall phenomenon labelled “Personalized Medicine”. Pharmacogenetic journals founded at the beginning of the twen
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Use of Biomarkers for the Prediction of Treatment Response: Immunoadsorption in Dilated Cardiomyopatse. We report findings from a pilot study that investigated the hemodynamic effects of a novel treatment option, immunoadsorption with subsequent IgG substitution (IA/IgG), in patients with dilated cardiomyopathy. Several previous studies have shown that this treatment leads to a significant improve
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Informed Consent in GANI_MED—A Sectional Design for Clinical Epidemiological Studies Within Individumarkers for specific diseases through the use of data from clinical treatments. From a research ethical point of view it needs to be noted that respective studies are mostly very complex. Therefore a variety of different normative requirements of both ethical and legal natures need to be met. On the
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