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Titlebook: Indacaterol; The First Once-daily Alexandre Trifilieff Book 2014 Springer Basel 2014 Asthma.Beta-2-Agonists.Bronchitis.Bronchodilatator.Lun

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发表于 2025-3-21 19:01:06 | 显示全部楼层 |阅读模式
书目名称Indacaterol
副标题The First Once-daily
编辑Alexandre Trifilieff
视频video
概述Summarizes preclinical and clinical data.A valuable source of information for scientists and clinicians.Contemporary monograph on the pharmacotherapy of COPD.Includes supplementary material:
丛书名称Milestones in Drug Therapy
图书封面Titlebook: Indacaterol; The First Once-daily Alexandre Trifilieff Book 2014 Springer Basel 2014 Asthma.Beta-2-Agonists.Bronchitis.Bronchodilatator.Lun
描述.Chronic obstructive pulmonary disease (COPD) is a multi-component condition that results in increasingly limited airflow, usually associated with an abnormal inflammatory response of the lung. It constitutes a major public health burden worldwide, while only very few effective therapies are available..This book provides a comprehensive overview of the development of Onbrez Breezhaler, a newly approved once-daily inhaled β2 agonist for the treatment of COPD. It reviews the current pharmacotherapy for COPD and discusses topics such as the chemical design and the pre-clinical pharmacology of the molecule, the early clinical development, the INHANCE study (which provides a successful example of the use of an adaptive design in the confirmatory setting) and the Phase III clinical efficacy study, as well as the history and performance of the Breezhaler device. Finally, a list of emerging targets is included that could well offer future treatment options for COPD..
出版日期Book 2014
关键词Asthma; Beta-2-Agonists; Bronchitis; Bronchodilatator; Lung function
版次1
doihttps://doi.org/10.1007/978-3-0348-0709-8
isbn_ebook978-3-0348-0709-8Series ISSN 2296-6056 Series E-ISSN 2296-6064
issn_series 2296-6056
copyrightSpringer Basel 2014
The information of publication is updating

书目名称Indacaterol影响因子(影响力)




书目名称Indacaterol影响因子(影响力)学科排名




书目名称Indacaterol网络公开度




书目名称Indacaterol网络公开度学科排名




书目名称Indacaterol被引频次




书目名称Indacaterol被引频次学科排名




书目名称Indacaterol年度引用




书目名称Indacaterol年度引用学科排名




书目名称Indacaterol读者反馈




书目名称Indacaterol读者反馈学科排名




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发表于 2025-3-21 23:09:29 | 显示全部楼层
The Early Clinical Development of Indacaterol,elopment of indacaterol confirmed preclinical data characterizing indacaterol as a long-acting β.-agonist with a sustained 24 h duration of bronchodilation, thus suitable for once-daily dosing, a rapid onset of action and a favourable safety profile over a range of dosages and delivery modes, both in asthma and COPD patients of various severities.
发表于 2025-3-22 02:04:31 | 显示全部楼层
Current Pharmacotherapy for COPD, a role limited to the severe and very severe patient with frequent exacerbations. Recent evidence suggests that maintenance antibiotic therapy may be additive to the effect of bronchodilators in reducing exacerbation frequency. The choice of agents may be based primarily on individual response, cost, side-effect profile, and availability.
发表于 2025-3-22 07:38:18 | 显示全部楼层
The Preclinical Pharmacology of Indacaterol,o systems as well as a large cohort of COPD patients, no association could be demonstrated between β.-adrenoceptor polymorphisms and indacaterol response. In conclusion, the preclinical profile of indacaterol suggests that this compound has a duration of action compatible with once-daily dosing in human, together with a fast onset of action.
发表于 2025-3-22 09:59:17 | 显示全部楼层
发表于 2025-3-22 13:45:41 | 显示全部楼层
2296-6056 cotherapy of COPD.Includes supplementary material: .Chronic obstructive pulmonary disease (COPD) is a multi-component condition that results in increasingly limited airflow, usually associated with an abnormal inflammatory response of the lung. It constitutes a major public health burden worldwide,
发表于 2025-3-22 20:27:58 | 显示全部楼层
Indacaterol978-3-0348-0709-8Series ISSN 2296-6056 Series E-ISSN 2296-6064
发表于 2025-3-22 22:43:48 | 显示全部楼层
https://doi.org/10.1007/978-3-0348-0709-8Asthma; Beta-2-Agonists; Bronchitis; Bronchodilatator; Lung function
发表于 2025-3-23 04:12:21 | 显示全部楼层
Alexandre TrifilieffSummarizes preclinical and clinical data.A valuable source of information for scientists and clinicians.Contemporary monograph on the pharmacotherapy of COPD.Includes supplementary material:
发表于 2025-3-23 07:55:35 | 显示全部楼层
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