书目名称 | Indacaterol |
副标题 | The First Once-daily |
编辑 | Alexandre Trifilieff |
视频video | |
概述 | Summarizes preclinical and clinical data.A valuable source of information for scientists and clinicians.Contemporary monograph on the pharmacotherapy of COPD.Includes supplementary material: |
丛书名称 | Milestones in Drug Therapy |
图书封面 |  |
描述 | .Chronic obstructive pulmonary disease (COPD) is a multi-component condition that results in increasingly limited airflow, usually associated with an abnormal inflammatory response of the lung. It constitutes a major public health burden worldwide, while only very few effective therapies are available..This book provides a comprehensive overview of the development of Onbrez Breezhaler, a newly approved once-daily inhaled β2 agonist for the treatment of COPD. It reviews the current pharmacotherapy for COPD and discusses topics such as the chemical design and the pre-clinical pharmacology of the molecule, the early clinical development, the INHANCE study (which provides a successful example of the use of an adaptive design in the confirmatory setting) and the Phase III clinical efficacy study, as well as the history and performance of the Breezhaler device. Finally, a list of emerging targets is included that could well offer future treatment options for COPD.. |
出版日期 | Book 2014 |
关键词 | Asthma; Beta-2-Agonists; Bronchitis; Bronchodilatator; Lung function |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-0348-0709-8 |
isbn_ebook | 978-3-0348-0709-8Series ISSN 2296-6056 Series E-ISSN 2296-6064 |
issn_series | 2296-6056 |
copyright | Springer Basel 2014 |