书目名称 | In Situ Hybridization: Medical Applications | 编辑 | G. R. Coulton,J. Belleroche | 视频video | http://file.papertrans.cn/463/462993/462993.mp4 | 图书封面 |  | 描述 | In situ hybridization has developed as a means of localizingspecific DNA and RNA sequences within tissues. The great strength ofthis approach is the ability to relate the distribution of specificnucleic acids with cell structures and the protein products of thetarget gene by means of immunohistochemistry. Complementary DNA, RNAor oligonucleotide probes, suitably labelled, are hybridized tospecific DNA or RNA targets within tissues. The spatial informationthus obtained has contributed greatly to our understanding of suchdiverse areas of research as gene mapping, viral infection,cytogenetics, protein synthesis, prenatal diagnosis and tissuegrafting. .This book is not intended as another recipe book, although it doesdescribe theoretical and practical aspects of the technology. Rather,the authors critically describe the contribution made by in situhybridization to specific areas of medical research. . | 出版日期 | Book 1992 | 关键词 | Chromosom; DNA; genetics; hybridization; tissue | 版次 | 1 | doi | https://doi.org/10.1007/978-94-011-2984-8 | isbn_softcover | 978-94-010-5326-6 | isbn_ebook | 978-94-011-2984-8 | copyright | Springer Science+Business Media Dordrecht 1992 |
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