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Titlebook: Immunomodulation; New Frontiers and Ad H. Hugh Fudenberg,H. D. Whitten,Fabio Ambrogi Book 1984 Plenum Press, New York 1984 antibody.antigen

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Modulation of Human T-Lymphocyte Mitogenesis by Interleukin 1 and Glucocorticoidscognized and may constitute an important mechanism by which glucocorticoids can act as immunomodulatory factors. Furthermore, this inhibitory action on lymphocyte mitogenesis seems to be not mediated by an on/off mechanism since both the presence of accessory cells (monocytes/macrophages) and the mi
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Functional Analysis of Alloreactive Helper T Cells Involved in the Induction of Cytolytic T Cell Resnse is initiated in which antigen specific cytotoxic T lymphocytes (CTL) are generated. The induction of CTL, however, requires the collaboration between functionally distinct T cell subpopulations. and accessory cells from the macrophage lineage, including dendritic cells. The experimental data acc
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Comparative Morphologic Changes in Canine and Human Breast Adenocarcinoma After Treatment with Plasmtumor cells within 24 hr after treatment consistent with lethal and sublethal changes. The lesions were unique in that they were not accompanied by inflammatory cell infiltration around damaged tumor cells. With further treatments in humans, more pronounced degenerative changes in individual tumor c
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Differential ,, Effects of Adenosine and Deoxyadenosine on Human T- and B-Lymphocyte Functioned cells. This inhibition might be secondary to a blockade of either the B cell or the T-helper cell activity, or to enhancement of T-suppressor activity. We favor the latter possibility. Deoxyadenosine in combination with EHNA enhances IgG secretion at low concentrations, whereas higher concentrati
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Functional Analysis of Alloreactive Helper T Cells Involved in the Induction of Cytolytic T Cell Resector cells, however, requires another soluble helper factor, distinct from Il-2 and provisionally named cytotoxic T cell differentiation factor (CTDF).. As with CTLp the activation of HTL-precursors (THTLp) also requires the appropriate antigen recognition by clonally distributed receptors. Upon bi
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Book 1984ogically inert, will have some modulating effects on immunity. From the coarse adjustment of antibody feedback inhibition upon cellular limnunity to the subtle finesse envisioned in Jerne‘s idiotypic network and s‘lppressor T cells, immunomodulators attempt to either magnify or diminish those respon
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