Titlebook: Immunological Tolerance; Methods and Protocol Paul J. Fairchild Book 2007 Humana Press 2007 AIDS.Antigen.Immunologie.Thymus.Transplantation

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Maria Foti,Paola Ricciardi-Castagnoli,Francesca Granuccitive tools to address policy problemsRising sea levels and altered weather patterns are expected to significantly alter coastal and inland environments for humans, infrastructure and ecosystems. Potential land-use changes and population increases, coupled with uncertain predictions for sea level ris

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Kathleen F. Nolan,Stephen P. Cobbold,Herman Waldmannations for nature conservancies, vegetation mapping, plannin.Deserts are unique ecosystems with their own biotic and abiotic components, and are often rich in renewable natural resources, the appropriate management of which can contribute significantly to the sustainable management of desert regions

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Frontiers of Immunological Toleranceantigens. We also consider the properties of naturally arising and other populations of regulatory T cells (Treg), together with growing evidence that interplay between DCs and Treg cells can sustain antigen-specific tolerance. B-cell tolerance and the role of hematopoietic cell chimerism in the ind

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Balancing Tolerance and Immunityof the mechanisms responsible for these phenomena has advanced significantly in recent years, we are still lacking a fully integrated model of how dendritic cell phenotype correlates with function, and how complex interactions with multiple dendritic and T cell subpopulations shape the course of the

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Differentiation of Dendritic Cell Subsets from Mouse Bone Marrow immune responses against pathogens and tumor cells. DC not only activate lymphocytes, but can also educate T cells to tolerate self-antigens, thereby minimizing autoimmune reactions. Another peculiarity of the DC system is the large variety of subsets described, both in the human and in the mouse,

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Genetic Modification of Dendritic Cells Through the Directed Differentiation of Embryonic Stem Cellspecific attenuation through the induction of immunological tolerance. Nevertheless, as terminally differentiated cells of the myeloid lineage, DC share with macrophages an inherent resistance to genetic modification, greatly restricting strategies available for studying their physiology and function

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Generation of Immunocompetent T Cells from Embryonic Stem Cellsates. Hematopoietic progenitors derive from the mesoderm, which gives rise to hemangioblasts that can differentiate into endothelial or endocardial precursors, or hematopoietic stem cells (HSCs). These HSCs, in turn, may either self-renew or differentiate into lineage-restricted progenitors, and ult