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Titlebook: Immunity to and Prevention of Herpes Zoster; Anne A. Gershon,Ann M. Arvin,Charles H. Calisher Conference proceedings 2001 Springer-Verlag

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发表于 2025-3-21 19:45:49 | 显示全部楼层 |阅读模式
书目名称Immunity to and Prevention of Herpes Zoster
编辑Anne A. Gershon,Ann M. Arvin,Charles H. Calisher
视频video
丛书名称Archives of Virology. Supplementa
图书封面Titlebook: Immunity to and Prevention of Herpes Zoster;  Anne A. Gershon,Ann M. Arvin,Charles H. Calisher Conference proceedings 2001 Springer-Verlag
描述Under sponsorship of the National Institutes of Health of Japan, an international conference entitled "Immunity and Prevention of Herpes Zoster" was held in 1 Osaka, Japan, March 8-10, 1999. Attendees included basic and clinical investi­ gators from Asia, Europe, and North America. The meeting was organized to explore progress made in basic virology and molecular understanding of varicella zoster (VZV), and to provide information on current knowledge of latency of VZV in humans. Updates on the immunology responses of humans to VZV, and a description of the current status of varicella vaccine worldwide were also included. In addition, the possibility of prevent­ ing zoster in people latently infected with wild-type VZV by immunizing them with varicella vaccine was presented. The papers in this volume include written summaries of most of the presentations given at that conference. Coincidentally but appropriately, the conference marked the twenty-fifth or "silver anniversary" of the first publication of the development and use of live varicella vaccine to prevent varicella, by Takahashi and his colleagues. Because varicella vaccine is the first herpesvirus vaccine licensed in use for
出版日期Conference proceedings 2001
关键词Gürtelrose; Herpes zoster; Impfung; Infektion; infection; virus
版次1
doihttps://doi.org/10.1007/978-3-7091-6259-0
isbn_softcover978-3-211-83555-5
isbn_ebook978-3-7091-6259-0Series ISSN 0939-1983
issn_series 0939-1983
copyrightSpringer-Verlag Wien 2001
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发表于 2025-3-21 21:51:07 | 显示全部楼层
Varicella-zoster virus with a lost gE epitope: evidence for immunological pressure by the human anthe predominant VZV glycoprotein; gE is a typical type 1 transmembrane protein with 623 amino acids. Recently, a variant virus was discovered which has a mutation in gE codon 150; this mutation converts an aspartic acid into an asparagine residue.
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Vaccination against cytomegalovirus,, particularly in pregnant women, who may transmit the virus to their offspring, with a high risk of mental retardation and deafness. Various experimental vaccines are in development, ranging from live, attenuated HCMV, subunit envelope glycoprotein, poxvirus vectors with CMV genes inserted, and plasmid DANN.
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978-3-211-83555-5Springer-Verlag Wien 2001
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Immunity to and Prevention of Herpes Zoster978-3-7091-6259-0Series ISSN 0939-1983
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The current status of live attenuated varicella vaccine,l-mediated immune response to the virus, zoster may be decreased. Varicella vaccine is predicted to have a major impact on the epidemiology of varicella and zoster in countries with high vaccine uptake.
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Biologic and geographic differences between vaccine and clinical varicella-zoster virus isolates,ther susceptible contacts, establishment of latency, and in some individuals, re­activation with the clinical picture of zoster. Infection with the vaccine strain results in the development of a protective immune response, minimal rash in a minority of individuals, rare transmission to other suscept
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Comparison of DNA sequence and transactivation activity of open reading frame 62 of Oka varicella vrs. These data suggest that gene 62 might have an important role for attenuation of VZV. This is the first report in which many substitutions of nucleotides in gene 62 of Oka vaccine virus was found, compared with that of Oka parental virus.
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