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Titlebook: Immediate Early Genes in Sensory Processing, Cognitive Performance and Neurological Disorders; Raphael Pinaud,Liisa A. Tremere Book 2006 S

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书目名称Immediate Early Genes in Sensory Processing, Cognitive Performance and Neurological Disorders
编辑Raphael Pinaud,Liisa A. Tremere
视频video
概述Provides a compilation of the most up-to-date literature on the topic of immediate early genes (IEGs), by the leading authors of the field of molecular neuroscience.Includes supplementary material:
图书封面Titlebook: Immediate Early Genes in Sensory Processing, Cognitive Performance and Neurological Disorders; Raphael Pinaud,Liisa A. Tremere Book 2006 S
描述.Immediate early genes (IEGs) are a class of genes that are rapidly expressed without new protein synthesis and, in most cases, in direct response to synaptic input. The most widely studied IEGs in neurobiology encode transcription factors, with two popular examples being .c-fos. and NGFI-A (a.k.a., .zif268 , egr-1, krox-24. and .zenk.). The activity-dependent expression of most inducible transcription factors has enabled neuroscientists to use their expression as mapping tools for neuronal activation, thereby enhancing our understanding of the anatomical and functional organization of the central nervous system (CNS). IEGs, however, are known to encode not only transcription factors, but a much wider variety of proteins including signaling molecules, growth factors and cytoskeletal proteins. IEGs are therefore both directly and indirectly implicated in the dynamic functional and anatomical restructuring of the CNS that permits the rapid integration of new sensory experience with pre-existing or on-going neural function. Finally, recent evidence suggests that IEGs may also be implicated in the initiation or amplification of aberrant signaling in connection with neuropathological di
出版日期Book 2006
关键词Alzheimer; Nervous System; Parkinson; cortex; neural network; neurobiology; regulation
版次1
doihttps://doi.org/10.1007/978-0-387-33604-6
isbn_softcover978-1-4899-8743-3
isbn_ebook978-0-387-33604-6
copyrightSpringer-Verlag US 2006
The information of publication is updating

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