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Titlebook: Hypertension and the Brain as an End-Organ Target; Hélène Girouard Book 2016 Springer International Publishing Switzerland 2016 aging.brai

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发表于 2025-3-21 20:01:21 | 显示全部楼层 |阅读模式
书目名称Hypertension and the Brain as an End-Organ Target
编辑Hélène Girouard
视频video
概述First overview to look at the effects of hypertension on the brain.Looks at both humans and animal models.Insight from studies using a variety of in vivo and in vitro methods
图书封面Titlebook: Hypertension and the Brain as an End-Organ Target;  Hélène Girouard Book 2016 Springer International Publishing Switzerland 2016 aging.brai
描述.The first comprehensive overview of the effects of hypertension on the brain. The book discusses not only the relationship between hypertension and stroke, but also the much less studied relationship between hypertension and cognitive decline and neurodegenerative diseases such as Alzheimer‘s. It seeks to answer two important questions. First, what are the conditions under which hypertension is associated with stroke, cognitive decline, and neurodegenerative disease? And second, what are the biological mechanisms by which hypertension alters brain homeostasis? By looking at the biological mechanisms of these relationships, this book provides insight to neuroscientists and neurologists regarding why anti-hypertension treatments make a big difference in the case of stroke, but have very little impact on cognitive decline and brain aging..
出版日期Book 2016
关键词aging; brain imaging; cerebrovascular; dementia; hypertension
版次1
doihttps://doi.org/10.1007/978-3-319-25616-0
isbn_softcover978-3-319-79815-8
isbn_ebook978-3-319-25616-0
copyrightSpringer International Publishing Switzerland 2016
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发表于 2025-3-21 23:23:27 | 显示全部楼层
Hélène GirouardFirst overview to look at the effects of hypertension on the brain.Looks at both humans and animal models.Insight from studies using a variety of in vivo and in vitro methods
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978-3-319-79815-8Springer International Publishing Switzerland 2016
发表于 2025-3-22 10:52:13 | 显示全部楼层
A Systematic Review of Reviews to Examine the Association Between Hypertension and Cognitive Impairsessed the methodological quality of the included reviews using the .ea.urement .ool to .ssess Systematic .eviews (AMSTAR) tool...: We included four meta-analyses and one systematic review. Results suggested small associations between hypertension and global cognition, episodic memory, and attention
发表于 2025-3-22 15:19:02 | 显示全部楼层
Hypertension and Age-Related Cognitive Decline,rtensive drug treatments report diverging results, but tend to suggest that treatment might be effective in preventing cognitive decline associated with age. Together, findings summarized here suggest that hypertension is an important factor that has a worsening effect on cognition as people age, an
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The Effects of Hypertension on Cerebral Artery Structure and Function, and Cerebral Blood Flow,leads to increases in myogenic tone and impaired dilation. Dysfunction of ion channels, including calcium-activated potassium channels and transient receptor potential (TRP) V4 channels, has also been associated with impaired endothelial function in hypertensive models. Understanding the mechanisms
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