书目名称 | Hydration Structures of Proteins |
副标题 | Atomic Details |
编辑 | Masayoshi Nakasako |
视频video | http://file.papertrans.cn/431/430249/430249.mp4 |
概述 | Introduces theories, experiments, and simulations, discussed in connection with each respective study.Discusses the influences of hydration structures of proteins on protein function and dynamics.Is p |
丛书名称 | Soft and Biological Matter |
图书封面 |  |
描述 | .This book describes hydration structures of proteins by combining experimental results with theoretical considerations. It is designed to introduce graduate students and researchers to microscopic views of the interactions between water and biological macromolecules and to provide them with an overview of the field. Topics on protein hydration from the past 25 years are examined, most of which involve crystallography, fluorescence measurements, and molecular dynamics simulations...In X-ray crystallography and molecular dynamics simulations, recent advances have accelerated the study of hydration structures over the entire surface of proteins. Experimentally, crystal structure analysis at cryogenic temperatures is advantageous in terms of visualizing the positions of hydration water molecules on the surfaces of proteins in their frozen-hydrated crystals. A set of massive data regarding hydration sites on protein surfaces provides an appropriate basis, enabling us to identify statistically significant trends in geometrical characteristics. Trajectories obtained from molecular dynamics simulations illustrate the motion of water molecules in the vicinity of protein surfaces at suffici |
出版日期 | Book 2021 |
关键词 | Cryogenic X-ray crystallography; Dynamics of protein hydration; Fluorescence measurement; Hydration str |
版次 | 1 |
doi | https://doi.org/10.1007/978-4-431-56919-0 |
isbn_ebook | 978-4-431-56919-0Series ISSN 2213-1736 Series E-ISSN 2213-1744 |
issn_series | 2213-1736 |
copyright | Springer Japan KK, part of Springer Nature 2021 |