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Titlebook: Human Tumour Xenografts in Anticancer Drug Development; Benjamin Winograd,Michael Peckham,Herbert Michael Conference proceedings 1988 Spr

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发表于 2025-3-21 20:03:26 | 显示全部楼层 |阅读模式
书目名称Human Tumour Xenografts in Anticancer Drug Development
编辑Benjamin Winograd,Michael Peckham,Herbert Michael
视频video
丛书名称ESO Monographs
图书封面Titlebook: Human Tumour Xenografts in Anticancer Drug Development;  Benjamin Winograd,Michael Peckham,Herbert Michael  Conference proceedings 1988 Spr
描述Starting in 1986, the European School of Oncology has expanded its activities in post­ graduate teaching, which consisted mainly of traditional disease-orientated courses, by promoting new educational initiatives. One of these is the cloister seminars, short meet­ ings intended for highly qualified oncologists and dealing with specific, controversial aspects of clinical practice and research. Another is the institution of permanent study groups, also called task forces, where a limited number of leading experts are invited to meet once a year with the aim of defining the state of the art and possibly reaching a consensus on developments and treatment in specific fields of oncology. This series of ESO Monographs was designed with the specific purpose of disseminat­ ing the results of the most interesting of the seminars and study groups, and providing concise and updated reviews of the subjects discussed. It was decided to keep the layout very simple in order to keep costs to a minimum and make the monographs available in the shortest possible time, thus overcoming a com­ mon problem in medical literature: that of the material being outdated even before publication. Umberto Veronesi
出版日期Conference proceedings 1988
关键词Antigen; biochemistry; carcinoma; interferon; transplantation
版次1
doihttps://doi.org/10.1007/978-3-642-73252-2
isbn_softcover978-3-642-73254-6
isbn_ebook978-3-642-73252-2
copyrightSpringer-Verlag Berlin Heidelberg 1988
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Representativity of Xenografts for Clinical Cancer. Tumor and Host Characteristics as Variables of Titution are factors of importance. Subcutaneous inoculation of tumor tissue is practical for most purposes, but “orthotopic” growth may be more clinically relevant for some tumors. New metastasis models have become available that permit biology and chemosensitivity studies to be performed under cond
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Comparison of Tumor Response in Nude Mice and in Patientsm. Xenografts enabled correct predictions for resistance in 96% and for tumor response in 90% of cases. Despite great efforts to obtain a large number of comparisons, only 32 test results were available before the patients needed treatment. Therefore, our study has shown that the xenograft system wi
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Activity of Conventional Drugs in Head and Neck Cancer Xenograftstal dose was used. The activity of methotrexate in the nude mouse is less than can be expected from clinical studies. The mechanism responsible for this lack of activity is discussed in relation to our recent results.
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B. J. M. Braakhuis,A. Leyva,H. M. Pinedo,G. B. Snow
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Benjamin Winograd,Michael Peckham,Herbert Michael
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