| 书目名称 | Human Trophoblast Neoplasms | | 编辑 | Roland A. Pattillo,Robert O. Hussa | | 视频video | | | 丛书名称 | Advances in Experimental Medicine and Biology | | 图书封面 |  | | 描述 | This book addresses neoplasms of the human trophoblast. The scant literature available on the epidemiology of trophoblast neoplasms suggests that they are as much as ten times more common in Africa, Asia, India, and much of the developing world than in Western countries. The stimulus for the book evolved out of a common interest to combine Western technology with the clinical experience in the developing world in a common pursuit of the study and eradication of trophoblast neoplasia. There is substantial evidence to contend that gene derepression as seen in trophoblastic disease may be a universal prerequisite to neoplastic transformation in general. The recent discovery that the tumor markers, human chorionic gonadotropin (hCG) or its subunits, are identifiable in over 90 percent of all extracted neoplasms suggests a critical role for this common denominator of gene derepression in neoplasia. This gene derepression concept in reproductive biology and neoplasia spans many of the basic parameters of human cell replication as related to endocrinology, immunology, biochemistry, electrophysiol ogy, genetics, and pharmacology. The International Society for the Study of Trophoblastic Di | | 出版日期 | Book 1984 | | 关键词 | cell; endocrinology; epidemiology; genetics; pharmacology; tumor | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4684-4811-5 | | isbn_softcover | 978-1-4684-4813-9 | | isbn_ebook | 978-1-4684-4811-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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发表于 2025-3-21 18:47:09
