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Titlebook: Hepatitis E Virus; Youchun Wang Book 2023Latest edition The Editor(s) (if applicable) and The Author(s), under exclusive license to Spring

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Characteristics and Functions of HEV Proteins,region, three open reading frames (ORFs), and a 3′ non-coding region. ORF1 is diverse between genotypes and encodes the nonstructural proteins, which include the enzymes needed for virus replication. In addition to its role in virus replication, the function of ORF1 is relevant to viral adaption in
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Hepatitis E as a Zoonosis,abitats. Among all these genotypes, four (genotypes 3, 4, 7, and C1) of them are confirmed zoonotic causing sporadic human diseases, two (genotypes 5 and 8) were likely zoonotic showing experimental animal infections, and the other seven were not zoonotic or unconfirmed. These zoonotic HEV carrying
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Transmission of Hepatitis E Virus,ia and Africa are waterborne and spread through contaminated drinking water. The reservoir of HEV in developed countries is believed to be in animals with zoonotic transmission to humans, possibly through direct contact or the consumption of undercooked contaminated meat. And HEV transmission throug
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