Titlebook: Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics; Hae Won Kim,A. Gerson Greenburg Book 2013 Springer-Verla

得意人

小丑

From the Atmosphere to the Mitochondrion: The Oxygen Cascade mitochondria, and the means whereby this delivery is regulated and optimized for efficiency and the “survival” of the organism as a whole. This occurs in four sequential steps comprising 1. mass transport exchange of air into and out of the alveolar spaces; 2. . exchange of oxygen and carbon dioxid

北极人

Pathophysiology of Hemorrhagic Shock and Resuscitation derangement of the normal oxygen supply–demand balance, accumulation of the byproducts of anaerobic metabolism, and dysfunction of one or more organ system. In the case of massive hemorrhage, shock is due specifically to impaired oxygen delivery (VO.) secondary to both hypovolemia and anemia. Resto

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Allogeneic Blood Transfusion for Surgical and Traumatic Hemorrhagerationale for allogeneic red cell transfusion in surgical and traumatic hemorrhage in a hospital setting. A large number of patients have now been enrolled in clinical trials. This experience provides high quality evidence to inform the transfusion decision. A restrictive transfusion has been establ

青春期

persistence

Regulatory Framework for Hemoglobin-Based Oxygen Carrier Trialsues, mainly for treatment of shock due to blood loss. These products are being developed in order to treat blood loss when red blood cells are not available, as may occur on the battlefield or in civilian life when trauma occurs.

semiskilled

Inclement

Cellular-Type Hemoglobin-Based Oxygen Carriers to Mimic the Red Blood Cell Structuredevelopment of Hb-based oxygen carriers (HBOCs). The physiological significance of the RBC structure is undergoing reconsideration. Fundamentally, excessive native Hb molecules are toxic, but encapsulation can shield this toxic effect. Cellular type HBOCs of various kinds are developed using liposom

脱落

Recombinant Octameric Hemoglobins as Resuscitation Fluids in a Murine Model of Traumatic Brain Injurr . expression system and purified. They were used as resuscitation fluids in our unique mouse model of traumatic brain injury (TBI) combined with severe hemorrhagic shock (HS). A sulfhydryl group was introduced onto the surface of the α-subunits of rHb A by substituting Asn78 with cysteine. The rHb

敲诈

Liposome-Encapsulated Hemoglobin as an Artificial Oxygen Carrier: Technological Features, Manufacturess and large production costs have hindered the progress in its development and, subsequently, its advancement to practical applications. However, we have been persistently developing LEH as an analogue of red blood cells (RBCs) for its use as AOCs, and to this end we have constructed a Good Manufa