书目名称 | Hedgehog signaling activation in human cancer and its clinical implications | 编辑 | Jingwu Xie | 视频video | | 概述 | Presents up-to-date information in this exciting research area.Summarizes major advances made on hedgehog signaling mechanisms, activation of the pathway in various human cancer types.Highlights curre | 图书封面 |  | 描述 | .Understanding the role of hedgehog signaling in cancer is critically important for novel cancer therapeutics. The hedgehog pathway is a major pathway regulating cell differentiation, tissue polarity, stem cell maintenance and cell proliferation. It is known by now that activation of this pathway occurs in a variety of human cancer, including basal cell carcinomas (BCCs), medulloblastomas, leukemia, gastrointestinal, lung, ovarian, breast and prostate cancers. This book provides insightful views suitable for graduate students, medical students, undergraduate students, basic and clinical scientists, cancer patients as well as the general public. . | 出版日期 | Book 2011 | 关键词 | Ci; Drosophilia; G-Protein Effector Network; Gli; polypeptide ligand | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4419-8435-7 | isbn_softcover | 978-1-4899-9541-4 | isbn_ebook | 978-1-4419-8435-7 | copyright | Springer Science+Business Media, LLC 2011 |
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