Titlebook: Handbook of the Cerebellum and Cerebellar Disorders; Mario U. Manto,Donna L. Gruol,Roy V. Sillitoe Reference work 2022Latest edition Sprin

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Specification of the Cerebellar Territoryal axis into distinct domains, which generate subsets of cerebellar neurons according to their neurotransmitter phenotype. The roof plate marked by . expression is at the origin of choroid plexus cells but does not contribute neurons or glia to the cerebellum. The rhombic lip, marked by . expression

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Proneural Genes and Cerebellar Neurogenesis in the Ventricular Zone and Upper Rhombic Lipproneural genes in cerebellar neurogenesis. Of the proneural genes examined in this chapter, . plays a quintessential role in the specification and development of granule cells and other cerebellar glutamatergic neurons. Besides playing key roles at early stages in these early developmental events,

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Zones and Stripes: Development of Cerebellar Topographyo disperse, triggered by Reelin signaling pathway proteins, to form the adult stripe array..The chapter will begin with a brief overview of adult cerebellar topography, primarily focusing on the mouse cerebellum, and then discuss the cellular and molecular mechanisms that establish these remarkable

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Roof Plate in Cerebellar Neurogenesisnic hedgehog from the choroid plexus promote proliferation of progenitors in the cerebellar ventricular zone. This chapter discusses studies that established the roles of the 4th ventricle roof plate and the hindbrain choroid plexus in cerebellar neurogenesis and the molecular mechanisms of their ac

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