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Titlebook: Handbook of Platelet Physiology and Pharmacology; Gundu H. R. Rao Book 1999 Springer Science+Business Media New York 1999 Biomaterial.Calc

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GTP Binding Proteins in Platelets and relay a specific message that leads to a defined cellular response. The process that translates the stimulus-receptor interaction into an intracellular chemical message is termed signal transduction. Signal transduction pathways are involved in the regulation of cell function in four broad phys
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Platelet Cyclic Nucleotide Phosphodiesterasesand ticlopidine, which blocks the ability of ADP to inhibit stimulated adenyl cyclase. Both of these drugs have proven prophylactic uses in reducing the risk of thromboocclusive and thromboembolic complications for all major arterial beds in individuals with a previous history of such episodes. Cont
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Phospholipase A2 in Platelets. (TxA. ) formed from arachidonic acid (AA, ω-6) serves as an important intracellular mediator in platelet function (1–5). More specifically, TxA. appears more critical for platelet responses such as shape change, aggregation, secretion, phosphoinositide turnover, Ca. mobilization from intracellular
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